Treatment with vitamin C dissolves toxic protein aggregates in Alzheimer's...
Researchers at Lund University have discovered a new function for vitamin C. Treatment with vitamin C can dissolve the toxic protein aggregates that build up in the brain in Alzheimer's disease. The...
View ArticleRoad block as a new strategy for the treatment of Alzheimer's
Blocking a transport pathway through the brain cells offers new prospects to prevent the development of Alzheimer's. Wim Annaert and colleagues of VIB and K.U. Leuven discovered that two main agents...
View ArticleStudy reveals link between high cholesterol and Alzheimer's disease
People with high cholesterol may have a higher risk of developing Alzheimer's disease, according to a study published in the September 13, 2011, issue of Neurology, the medical journal of the American...
View ArticleScientists discover that specific antibodies halt Alzheimer's disease in mice
Antibodies that block the process of synapse disintegration in Alzheimer's disease have been identified, raising hopes for a treatment to combat early cognitive decline in the disease.
View ArticleRole of amyloid beta as sensors and protectors in Alzheimer's and other...
Alzheimer's disease is the sixth leading cause of death in the United States and the only cause of death among the top 10 in America without a way to prevent, cure or even slow its progression,...
View ArticleCarmustine decreases amyloid beta plaques
Long term treatment by carmustine, a chemical relative of mustard gas and already used to treat some types of brain cancer, can decrease the amount of amyloid β and number of amyloid plaques in a mouse...
View ArticleStudy unravels central mystery of Alzheimer's disease
Scientists at The Scripps Research Institute (TSRI) have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the...
View ArticleNew Alzheimer's research suggests possible cause: The interaction of proteins...
For years, Alzheimer's researchers have focused on two proteins that accumulate in the brains of people with Alzheimer's and may contribute to the disease: plaques made up of the protein amyloid-beta,...
View ArticleFighting Alzheimer's disease with protein origami
Alzheimer's disease is a progressive degenerative brain disease most commonly characterized by memory deficits. Loss of memory function, in particular, is known to be caused by neuronal damage arising...
View ArticleWhy don't we all get Alzheimer's disease?
Researchers at the University of California, San Diego School of Medicine offer an explanation for why we all don't get Alzeimer's disease (AD)—a trick of nature that in most people maintains critical...
View ArticleCopper identified as culprit in Alzheimer's disease
Copper appears to be one of the main environmental factors that trigger the onset and enhance the progression of Alzheimer's disease by preventing the clearance and accelerating the accumulation of...
View ArticleMonster mash: Protein folding gone wrong
Imagine a 1950s horror movie monster—a creeping, gelatinous, gluey tangle of gunk that strangles everything around it. That's what amyloid plaques are like when they form in body tissues. These gooey...
View ArticleEnzyme BACE1 may be important in predicting onset of Alzheimer disease
The critical enzyme beta-secretase1 (BACE1) is known to be elevated in brains with sporadic Alzheimer disease (AD). Scientists have now found increased levels of BACE1 in brains with mild cognitive...
View ArticleNew amyloid-reducing compound could be a preventive measure against Alzheimer's
Scientists at NYU Langone Medical Center have identified a compound, called 2-PMAP, in animal studies that reduced by more than half levels of amyloid proteins in the brain associated with Alzheimer's...
View ArticleResearchers find clue to stopping Alzheimer's-like diseases
(Medical Xpress)—Tiny differences in mice that make them peculiarly resistant to a family of conditions that includes Alzheimer's, Parkinson's and Creutzfeldt-Jakob Disease may provide clues for...
View ArticleNovel culture system replicates course of Alzheimer's disease, confirms...
An innovative laboratory culture system has succeeded, for the first time, in reproducing the full course of events underlying the development of Alzheimer's disease. Using the system they developed,...
View ArticleCompound reverses symptoms of Alzheimer's disease in mice, research shows
A molecular compound developed by Saint Louis University scientists restored learning, memory and appropriate behavior in a mouse model of Alzheimer's disease, according to findings in the May issue of...
View ArticleGenetically engineered mice that more accurately reproduce the conditions of...
Potential therapies for Alzheimer's disease are currently studied using genetically engineered mouse strains that display many of the key features of the disease. Most of these mouse models overexpress...
View ArticleNew study links Alzheimer's to brain hyperactivity
Patients with Alzheimer's disease run a high risk of seizures. While the amyloid-beta protein involved in the development and progression of Alzheimer's seems the most likely cause for this neuronal...
View ArticleNew technology reveals insights into mechanisms underlying amyloid diseases
Amyloid diseases, such as Alzheimer's disease, type 2 diabetes, cataracts, and the spongiform encephalopathies, all share the common trait that proteins aggregate into long fibers which then form...
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